Is the Early Cancer Detection Blood Test Worthwhile?

OncoK9 recommends screening for giant and high-risk breeds at younger ages.
OncoK9’s recommended ages to start cancer screening

If you’ve been in a vet office lately, you might have seen a brochure advertising the OncoK9 blood test, an early-detection cancer screening test.

I first heard of it when I took Cali to a specialist who ended up diagnosing her hemangiosarcoma. By then, we had done the ultrasounds and were on our way to the splenectomy, so I didn’t “need” the test; I knew she had cancer.

The blood test “uses a simple blood draw to detect abnormal DNA released into circulation by cancer cells,” and claims to be able to pick up on these markers before the dog would be likely to have any symptoms. Dogs with some cancers, like hemangiosarcoma, rarely show any symptoms. OncoK9 is said to be able to detect 30 different types of cancer, including several very common canine cancers.

The company recommends it annually for dogs aged 7 and older, with different guidelines for cancer-prone breeds. They suggest starting screening at age 6 for goldens, for example, and age 4 for boxers (see illustration above).

Should you do it?

I can’t answer that, but I can share the pros and cons I see.

An argument for doing the test is that early detection gives you the best chance to treat some cancers.

Now for the “cons.” The test detects cancer markers, or claims to, but it does not give any indication of the type or location of the cancer.

A friend who works for a vet in another state reports that her clinic looked into the test, and her vet worries about the high potential for false negatives — not catching the presence of cancer markers — as well as the smaller, but still present, chance of false positives. Paired with the lack of indication of what type of cancer the dog has, a false positive could send a family on a very costly, stressful wild goose chase to try to identify the nonexistent cancer.

This vet says the test “might be helpful” for a dog with unexplained weight loss and no other evidence of disease; that’s far from a blanket recommendation for an annual check!

Finally, the cost: The test costs $500 at my specialty clinic. Cost will vary by location, but it’s not an inexpensive test. A few hundred dollars (or more) is a hefty addition to your dog’s annual checkup, and it’s unlikely that pet insurance would cover it.

My specialist vet’s office told me that, following a positive test, the next steps would be tests to figure out the type and stage of the cancer. And that anyone with a positive test gets a $1,000 credit toward that testing. I assume that this is because the company that does the OncoK9 test uses the follow-up and test data to refine the test and/or to work on treatments. Either way, the hefty sum tells me that a) the follow-up testing is pricey and b) they don’t expect a huge proportion of positives.

What do you DO with a positive result?

That raises the next obvious question, which is: If I were to get a positive test result, what would I do?

  • If you are not prepared to go down the expensive route of testing to identify and stage the cancer, then treat it … I’m not sure what you gain by doing the test.
  • If you are, and you have a dog of a breed that is likely to get cancer, then early detection and treatment could give you more time with your dog and/or lead you to an early treatment that spares your dog some suffering, depending of course on what additional testing you did, how quickly you identified the dog’s cancer, and whether it was a treatable cancer — all significant questions.

Whether to do the test (and what to do afterward) is, of course is a very individual decision.

Orly is only 1. I am certainly hoping that we have more reliable, less costly ways to detect (early) and effectively treat canine cancer before she’s of an age where I’d face the question of whether to do this type of test. Cali spent her life helping to make that happen; and the many researchers working on canine cancer detection and treatment offer hope for future pups.

Morris Foundation Launches Hemangiosarcoma Initative

The Morris Foundation’s Golden Retriever Lifetime Study started enrolling dogs more than 10 years ago, a few months before Cali was born.

The Foundation recently sent an update with the sad news that they’re nearing the original endpoint of the study: 500 cancer diagnoses in Study dogs. They’re extending the endpoint and continuing the study.

Additional news that was a shock to me, despite close experience with hemagiosarcoma — three-quarters of the study dogs who have died had cancer … and 70% of the cancers were hemagiosarcoma.

So the Foundation is launching a ” multi-year, multi-million-dollar endeavor to dramatically change the story of hemangiosarcoma from one with an ending of almost certain death to one with a new beginning.”

Researchers can submit grant applications beginning in January.

Though Study Exam Day has never been a favorite day for Cali (or most of the “Heroes,” as participants are called), the study has gathered a vast amount of data that will help dogs of all breeds in many ways.

I’m hopeful that this initiative will find new ways to extend the lives of dogs with hemagiosarcoma.

Join the Fight Against Canine Cancer

Cali’s superhero cape was at the cleaners …

If you read last week’s post, you’ll know that canine cancer is on my mind. Not only Alberta’s, though. Cali, as many readers know, is a Hero. That’s what the Morris Animal Foundation calls participants in its Golden Retriever Lifetime Study.

Cali does her bit to fight cancer by “enduring” a very thorough annual physical, which is coming up next month. She blogged about  last year’s visit. She pretends it is awful, but the nonstop tail (and butt) wagging gives her away. Anything that involves that many cookies can’t be all bad.

Cali’s one of 3,000 goldens in this study. Morris started signing dogs up a few months before she was born. Two of her brothers are also in the study. The oldest dogs accepted were two years old. The study will examine a huge amount of data and try to identify genetic and environmental factors that lead to canine cancer.

Why am I saying all of this? Some of the participants, none of whom could be older than six, have already gotten cancer. Some are in remission; a few have died. I don’t know how many. I follow the experiences of participants whose humans post on the group’s Facebook page; it’s a very unscientific sample. Some participants have older sibling-supporters (like Jana!) and some of them, too, have died of cancer in the three and a half years that I have been part of this group.

It’s too much!

What can you do? Funny you should ask that …

You can register your dog for the draft. The Morris Animal Foundation Canine Lifetime Health Project draft, that is. It is a registry of dogs /  humans willing to participate in future studies. Morris is not registering for a specific study right now, but the re-opening of the registry might mean that they soon will be. It’s a chance for your dog to be a hero too. And for you to help fight this killer disease that takes too many of our dogs too soon, and causes millions more to suffer. In fact, their research is not limited to cancer, so your dog might be able to help researchers understand other serious canine illnesses.

Think about it. Take a look at the website. Cali, Alberta, and thousands of other dogs will thank you.